Acknowledgements

This work received funding by the European Research Council consolidator grant CODECHECK, under the European Union’s Horizon 2020 research and innovation programme (grant agreement 681443), Fundação para a Ciência e a Tecnologia of Portugal (PTDC/MED-ONC/3479/2020), and La Caixa Health Research Grant (LCF/PR/HR21/52410025) to Helder Maiato. We also thank Fundação para a Ciência e Tecnologia of Portugal for the Ph.D. fellowships SFRH/BD/130938/2017, SFRH/BD/117063/2016, and 2021.07945.BD, to Ana Margarida Gomes, Marco Novais-Cruz and Joana Macário Monteiro.